A groundbreaking chemical process has been developed that converts thiols and disulfides into sulfonyl fluorides using SHC5® and KF, advancing the field of “click chemistry” with efficiency and environmental friendliness. This green method produces minimal byproducts, making it a preferred option for chemical and industrial synthesis.

The idea of “click chemistry” is known for its precise and quick linking of molecules, making it widely used in various fields like materials science, chemical biology, and pharmaceuticals. However, the synthesis of sulfonyl fluoride, a crucial compound in certain reactions, was previously done using toxic and difficult-to-handle substances. This new process offers a safer and environmentally-friendly alternative using SHC5® and KF.

This innovative method allows for the tailored production of a wide range of sulfonyl fluorides, including various chemical groups. It is cost-effective, scalable, and simple, making it ideal for industrial use. The researchers behind this study emphasize the importance of developing sustainable synthetic methods for creating valuable compounds like pharmaceuticals. They aim to continue their research on green synthesis to benefit multiple industries.



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