The microbial enzyme iron nitrogenase shows a strong affinity for the greenhouse gas CO2, making it a promising candidate for future biotechnologies. Nitrogenases are essential enzymes that provide all forms of life with bioavailable nitrogen in the form of ammonia. Some nitrogenases can also convert CO2 into useful hydrocarbon chains, offering potential for biotechnological processes.

A team of researchers in Marburg, Germany, led by Johannes Rebelein from the Max Planck Institute, have investigated the substrate preferences of nitrogenase. They discovered that certain nitrogenases can efficiently reduce CO2 to produce valuable products such as methane and formic acid. This ability makes them a promising option for sustainable bioproduction.

The researchers studied two forms of nitrogenase in the bacterium Rhodobacter capsulatus: the molybdenum (Mo) nitrogenase and the iron (Fe) nitrogenase. They found that the Fe nitrogenase is three times more efficient at reducing CO2 compared to the Mo nitrogenase, which primarily focuses on converting N2 into ammonia.

Furthermore, the Fe nitrogenase showed a preference for CO2 over N2 when both substrates were available, highlighting its potential for CO2 reduction. The researchers also observed that Fe nitrogenase could convert CO2 into valuable products even without additional CO2 in the environment, suggesting that this process may be common in nature.

Overall, this study challenges the traditional view of nitrogenases as solely nitrogen-converting enzymes. The ability of certain nitrogenases to efficiently reduce CO2 opens up possibilities for utilizing them in carbon fixation and utilization processes. This could have significant implications for the development of sustainable technologies and the transition towards a circular economy.



Source

Tagged: